The effects of guanylate cyclase inhibitor ODQ on astrocytes cGMP and GFAP 鸟苷酸环化酶抑制剂ODQ对星形胶质细胞cGMP及GFAP的影响
The mechanism is probably that the consumption of cell mercapto lowers the activity of guanylate cyclase, thus weakening the slackness of blood vessel's smooth muscles. 其机制可能是,细胞巯基耗竭,使鸟苷酸环化酶活性降低,致血管平滑肌松弛作用减弱。
Modulation of cGMP levels, soluble guanylate cyclase and phosphodiesterase activities in brain of morphine dependent mice 吗啡依赖小鼠脑组织cGMP水平、鸟苷酸环化酶及磷酸二酯酶活性的调节
Expression Pattern of Soluble Guanylate Cyclase α 1 and β 1 Subunits in the Male Reproductive System of Rat 可溶性鸟苷酸环化酶α1和β1亚基在雄性大鼠生殖系统中表达的研究
NO exerted these effects through a pathway that does not involve guanylate cyclase and cGMP dependent protein kinase. NO这些作用通过的通路不涉及到鸟苷酸环化酶和cGMP依赖的蛋白激酶。
Atrial natriuretic peptide ( ANP) is a member of the natriuretic peptide family. By binding with its receptor and thereafter activating guanylate cyclase, ANP increases intracellular cGMP level and hence produces biological effects. 心房利钠肽属于利钠肽家族,其通过与受体结合激活鸟苷酸环化酶,促进细胞内环鸟苷酸水平升高而发挥生物学功能。
Study on soluble guanylate cyclase in pulmonary hypertension rat model 大鼠慢性缺氧高二氧化碳肺动脉高压模型可溶性鸟苷酸环化酶的表达
Changes of NO-and H_2O_2-dependent soluble guanylate cyclase pathway in the hypoxic hypercapnic pulmonary hypertension rats 肺动脉高压大鼠一氧化氮及过氧化氢依赖的可溶性鸟苷酸环化酶通路的变化
Objective To study the effects of methylene blue ( MB), a guanylate cyclase inhibitor, on hemodynamics and oxygenation in dog with septic shock. 目的观察鸟苷酸环化酶抑制药亚甲蓝(MB)对感染性休克犬血液动力学和氧合功能的影响。
The Modelling and Computation Analysis of the Soluble Guanylate Cyclase Heme Binding Domain 可溶性鸟苷酸环化酶的卟啉结合域结构模拟及计算分析
Expressions of Soluble Guanylate Cyclase α_1 and β_1 in Vascular Smooth Muscle after Cerebral Ischemia-reinfusion in Rats 可溶性鸟苷酸环化酶α1、β1在脑缺血再灌注后血管平滑肌中表达的实验研究
Objective To investigate the mRNA and protein expressions of soluble guanylate cyclase ( sGC) and its enzyme activity in pulmonary hypertension rat model which was reproduced by hypoxia and hypercapnia. 目的观察大鼠慢性缺氧高二氧化碳(CO2)肺动脉高压模型肺动脉可溶性鸟苷酸环化酶(sGC)的表达及其活性。
AIM: To investigate the expression of soluble guanylate cyclase protein and its mRNA in rat pulmonary artery after exposure to hypoxia and hypercapnia. 目的:探讨慢性低O2高CO2时大鼠肺动脉可溶性鸟苷酸环化酶(sGC)基因及其蛋白表达的变化。
Objective To explore the expressions of α 1 and β 1 subunits of the soluble guanylate cyclase ( sGC α 1, β 1) in the vascular smooth muscle after cerebral ischemia-reinfusion in rats and their significance. 目的探导可溶性鸟苷酸环化酶(sGC)α1、β1亚基蛋白在大鼠脑缺血再灌注后血管平滑肌中的表达及其意义。
Effects of hypoxia and hypercapnia on expression of soluble guanylate cyclase in rat pulmonary artery 低O2高CO2对大鼠肺中小动脉可溶性鸟苷酸环化酶基因及其蛋白表达的影响
Objective To observe the changes of plasma nitric oxide in rabbits with traumatic shock and the intervention of methylene blue ( MB), a guanylate cyclase inhibitor. 目的观察创伤性休克兔血浆一氧化氮(NitricOXide,NO)的动态变化及鸟苷酸环化酶抑制药亚甲蓝(methyleneblue,MB)的干预作用。